ARTICULAR MANIFESTATIONS OF ACROMEGALY
作者:
M. PODGORSKI,
B. ROBINSON,
A. WEISSBERGER,
J. STIEL,
S. WANG,
P. M. BROOKS,
期刊:
Australian and New Zealand Journal of Medicine
(WILEY Available online 1988)
卷期:
Volume 18,
issue 1
页码: 28-35
ISSN:0004-8291
年代: 1988
DOI:10.1111/j.1445-5994.1988.tb02236.x
出版商: Blackwell Publishing Ltd
关键词: Acromegaly;arthropathy;growth hormone
数据来源: WILEY
摘要:
Abstract:Forty‐five patients with acromegaly or gigantism were reviewed for musculoskeletal abnormalities. Abnormalities of peripheral joints occurred in 74% of the patients and spinal involvement in 47%, leading to significant morbidity. Joint abnormalities most frequently affected the large joints (hips, knees and shoulders) but the wrist and hand were also involved. The radiological features of acromegalic arthropathy are described, including vertical widening of the hip joint, enthesopathy and osteophytosis. A favourable response to treatment is associated with a less severe arthropathy and a good functional outcom
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