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Spectrophotometric Determination of Naproxen in Pure and Pharmaceutical Preparations

 

作者: Islam Ullah Khan,   Tehseen Aman,   Ambreen Ashraf,   Asrar A. Kazi,  

 

期刊: Analytical Letters  （Taylor Available online 1999）
卷期: Volume 32, issue 10  

页码: 2035-2050

 

ISSN:0003-2719

 

年代: 1999

 

DOI:10.1080/00032719908542950

 

出版商: Taylor & Francis Group

 

关键词: Spectrophotometer;naproxen;1-naphthylamine;sodium nitrite

 

数据来源: Taylor

 

摘要:

Naproxen reacts with 1-naphthylamine and sodium nitrite to give an orangish red colour having maximum absorbance at 460-480 nm (working wavelength 480 nm). The reaction is selective for naproxen with 0.001 mg/ml as visual limit of quantitation and provides a basis for a new spectrophotometric determination. The reaction obeys Beer's law from 0.01mg to 6.5 mg/10ml of naproxen and the relative standard deviation is 1.5%. The quantitative assessment of tolerable amount of other drugs is also studied.

 

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