Presence of Human Papillomavirus DNA in Benign and Precancerous Oral Leukoplakias and Squamous Cell Carcinomas
作者:
A. Gassenmaier,
O.P. Hornstein,
期刊:
Dermatology
(Karger Available online 1988)
卷期:
Volume 176,
issue 5
页码: 224-233
ISSN:1018-8665
年代: 1988
DOI:10.1159/000248710
出版商: S. Karger AG
关键词: Human papillomavirus DNA;Hybridization in situ;Oral benign and precancerous leukoplakias;Squamous cell carcinomas
数据来源: Karger
摘要:
A variety of benign squamous epithelial lesions of the mucosa are associated with human papiUomaviruses (HPV). Recently virus-specific DNA was also detected in oral invasive carcinomas. In sections of 373 formalin-fixed and paraffin-embedded samples taken from benign and precancerous leukoplakias and squamous cell carcinomas, HPV DNA could be identified in 56 specimens by in situ hybridization technique. The biological significance of viruses of the HPV group in the carcinogenesis of oral epithelial lesions is still unknown.
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