Immune adherence with keratinized human oral mucosa and human serum
作者:
TORE KRISTOFFERSEN,
HANS‐KRISTIAN KROGH,
期刊:
European Journal of Oral Sciences
(WILEY Available online 1971)
卷期:
Volume 79,
issue 1
页码: 31-39
ISSN:0909-8836
年代: 1971
DOI:10.1111/j.1600-0722.1971.tb01990.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
abstract–All normal human sera examined have been shown to contain complement‐fixing antibody to an antigen present in stratum corneum of human skin. By immune adherence with human sera and sections of frozen biopsy specimens, the antigen was found to be present in sections of keratotic and parakeratotic areas of human gingiva, tongue, alveolar, buccal, and palatal mucosa. Serum from biopsy donors mediated the adherence reaction. Absorption with a phenol‐water extract (water phase) of stratum corneum of skin removed the antibodies. The antigen was not detected in non‐keratinized areas of human oral mucosa, including gingival crevice and cuff epithelium. Erythrocytes also adhered to keratinized epithelium in gingival biopsy specimens fixed in ethanol and cleared in xylene at 4° C prior to sectioning and incubation with hum
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