Functional roles of membrane glycoprotein CD36
作者:
DavietLaurent,
McGregorJohn L.,
期刊:
Platelets
(Taylor Available online 1996)
卷期:
Volume 7,
issue 3
页码: 117-124
ISSN:0953-7104
年代: 1996
DOI:10.3109/09537109609023570
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Cell-cell and cell-extracellular matrix interactions are mediated by a number of membrane glycoproteins. On the basis of structural homologies, several families of cell adhesion molecules (integrins, selectins, immunoglobulins, cadherins, leucine-rich glycoproteins) have been established. Since 1991, a new family of CD36-like proteins has been identified. CD36 is a cell surface glycoprotein that interacts with a large variety of ligands. CD36 has been implicated in thrombosis, vascular biology, lipid metabolism and atherogenesis. In this review, we aim to summarize our present knowledge on this important, multifunctional glycoprotein.
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