From the stem bark ofMesua ferreabetulinic acid, (-)-epicatechin, 1,6-dihydroxyxanthone, pyranojacareubin and two novelbis-xanthones have been isolated. Thebis-xanthones were characterised, on the basis of 2D homo- and heteronuclear correlation NMR spectroscopy as (E)-2ξ-methyl-2ξ-{2-(2,7,9-trihydroxyxanthon-8-yl)ethen}-dioxan-({5,6c:2,3e-}-7-hydroxy-4,9-dimethoxyxanthone) (mesuabixanthone-A) and its monomethyl ether (E)-2ξ-methyl-2ξ-{2-(7,9-dihydroxy-2-methoxyxanthon-8-yl)ethen}-dioxan-({5,6c:2,3e}-7-hydroxy-4,9-dimethoxyxanthone) (mesuabixanthone-B).