Differences in the order of termination of DNA replication in human chromosomes in peripheral blood lymphocytes and skin fibroblasts from the same individual
作者:
R.A. Farber,
R.L. Davidson,
期刊:
Cytogenetic and Genome Research
(Karger Available online 1977)
卷期:
Volume 18,
issue 6
页码: 349-363
ISSN:1424-8581
年代: 1977
DOI:10.1159/000130781
出版商: S. Karger AG
数据来源: Karger
摘要:
A comparison of the sequence of terminal replication of DNA in human chromosomes has been made between skin fibroblasts and peripheral blood lymphocytes from the same adult male individual. The chromosomes were identified by quinacrine-banding, and the order of termination of replication was determined by autoradiography. Chromosomes 4, 5, 8, and 13 were found to terminate DNA replication later in lymphocytes than in fibroblasts, whereas chromosomes 15, 19, 20, and 22 were found to terminate their replication earlier in lymphocytes than in fibroblasts.
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