Combined Electroconvulsive-Clozapine Therapy
作者:
Marina Kupchik,
Baruch Spivak,
Roberto Mester,
Ilya Reznik,
Noah Gonen,
Abraham Weizman,
Moshe Kotler,
期刊:
Clinical Neuropharmacology
(OVID Available online 2000)
卷期:
Volume 23,
issue 1
页码: 14-16
ISSN:0362-5664
年代: 2000
出版商: OVID
关键词: Electroconvulsive therapy;Clozapine;Schizophrenia
数据来源: OVID
摘要:
We reviewed 36 reported psychiatric patients who were treated with a combination of electroconvulsive therapy (ECT) and clozapine. The indication of the ECT-clozapine treatment was resistance to classical antipsychotic agents, clozapine, or ECT alone. Sixty-seven percent of the patients benefited from the combined treatment. In most of the patients, the combined treatment was safe and well tolerated. Adverse reactions occurred in 16.6% of the patients and included prolonged ECT-induced seizures (one case), supraventricular (one case) and sinus tachycardia, and blood pressure elevation. It seems that combined ECT-clozapine treatment is effective and safe. This strategy may be a therapeutic option in treatment-resistant patients.
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