Experimental models of autoimmune diseases
作者:
DruetP.,
期刊:
Current Eye Research
(Taylor Available online 1990)
卷期:
Volume 9,
issue sup1
页码: 139-144
ISSN:0271-3683
年代: 1990
DOI:10.3109/02713689008999434
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Several experimental models of autoimmune diseases have been studied which often mimic the human situation. Autoreactive T cells that emerge either spontaneously or after immunization have been identified in several stiuations. The main lesson from these models is that these autoreactive T cells are negatively controlled in the normal situation and that a defect either inherited or acquired in this regulatory circuit is responsible for autoimmunity.
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