A Study of the Effect of AB0 Incompatible Plasma in Platelet Concentrates Transfused to Bone Marrow Transplant Recipients
作者:
A. Shanwell,
O. Ringdén,
B. Wiechel,
S. Rumin,
O. Âkerblom,
期刊:
Vox Sanguinis
(WILEY Available online 1991)
卷期:
Volume 60,
issue 1
页码: 23-27
ISSN:0042-9007
年代: 1991
DOI:10.1111/j.1423-0410.1991.tb00866.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
Abstract.Bone marrow transplant recipients at Huddinge Hospital have routinely received single‐donor platelet concentrates (PC) from blood group 0 donors. These PC contain approximately 350 ml plasma, which is incompatible with patients of group A, B and AB. In 27 patients transplanted with an ABO‐identical bone marrow, serological investigations have been performed every week after transplantation (median 6 weeks, range 3–14). Nine of 11 recipients with blood group A developed a positive direct antiglobulin test (DAT) after PC transfusions, while none of 15 patients of blood group 0 developed a positive DAT. Anti‐A could be eluted in DAT‐positive cases. In no case was there any clinical sign of hemolysis. Nor did recipients of groups A, B or AB (n = 34) require more red blood cells or PC transfusions compared to recipients of group 0
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