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Ketanserin and malignant hyperthermia in pigs

 

作者: H. ØRDING,   A. HALD,   E. SJØNTOFT,  

 

期刊: Acta Anaesthesiologica Scandinavica  （WILEY Available online 1986）
卷期: Volume 30, issue 1  

页码: 7-9

 

ISSN:0001-5172

 

年代: 1986

 

DOI:10.1111/j.1399-6576.1986.tb02356.x

 

出版商: Blackwell Publishing Ltd

 

关键词: Anaesthetics;halothane;malignant hyperthermia;neuromuscular relaxants;porcine stress syndrome;suxamethonium

 

数据来源: WILEY

 

摘要:

Four Danish landrace pigs susceptible to MH were challenged with halothane and suxamethonium on six occasions after pretreatment with the serotonin‐S2antagonist ketanserin 0.4 mg/kg (three animals) or 4 mg/kg (three animals). The animals developed typical MH on all occasions despite the pretreatment. Dantrolene remains the only specific drug for prevention and treatment of M

 

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