Propranolol for the Treatment of the Alcoholic Hangover
作者:
BoginRobert M,
NostrantTimothy T,
YoungMark J,
期刊:
The American Journal of Drug and Alcohol Abuse
(Taylor Available online 1986)
卷期:
Volume 12,
issue 3
页码: 279-284
ISSN:0095-2990
年代: 1986
DOI:10.3109/00952998609007397
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Hangover following consumption of alcohol includes many disagreeable signs and symptoms that are suggestive of sympathetic overactivity. We performed a randomized, double-blind, crossover controlled study to assess the effect of beta blockade in preventing the symptoms of hangover. Ten subjects were randomized to receive 160 mg of a long-acting preparation of propranolol or a placebo and then participated in a controlled drinking situation. Patients were then evaluated for symptoms and signs of hangover. The results showed that although beta blockade was achieved, there was no clinically important reduction in symptoms of hangover. We conclude that propranolol does not prevent the symptoms of hangover.
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