A summary of the results of regional flood frequency analyses that have been carried out in many tropical and sub-tropical countries is presented. The results provide a set of flood estimation methods which should be of immediate usefulness in practical applications, bearing in mind the errors of generalization. By defining the representative values of the mean annual flood and of the flood frequency curves for each region, an attempt has been made to develop relationships between the methods and climatic characteristics. These show that adequate relationships can be obtained based solely on the median annual average rainfall and the median catchment area for the regions. In particular, the steepness of the regional flood frequency curve can be estimated reasonably well from these two parameters. The relationships confirm that, broadly speaking, for humid regions the “average” flood—the flood that occurs regularly every one or two years—is relatively large, but the flood frequency curve is not very steep; rare floods (occurring once in every 100 to 1000 years) are not very much larger than the average flood. Conversely, in arid regions, the average flood is small, but rare floods can be extremely large multiples of the average. These relationships provide a useful initial indication of the type of regional flood frequency estimation method likely to be found in tropical and sub-tropical regions throughout the world.