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Non-Cytopathic, Non-Productive Infection by Herpes Simplex Viruses Types 1 and 2

 

作者: Barry Garfinkle,   Brian R. McAuslan,  

 

期刊: Intervirology  （Karger Available online 1973）
卷期: Volume 1, issue 5-6  

页码: 362-375

 

ISSN:0300-5526

 

年代: 1973

 

DOI:10.1159/000148865

 

出版商: S. Karger AG

 

关键词: Herpes simplex transformation;Latency;RSV;Thymidine kinase

 

数据来源: Karger

 

摘要:

When RSV-transformed rodent cells were infected with either HSV type 1 or 2, the cells were not killed, but continued to grow and divide for at least ten passages. The HSV genome was partially expressed in these cells. Thymidine kinase was elicited and its synthesis was controlled. Indirect evidence suggests that limited herpes viral DNA synthesis occurred. Some HSV antigens were synthesized but the infection was non-productive.

 

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