An earlier report described the presence of high concentrations of lead in the bovine eye. However, we have been unable to detect this heavy metal in the ocular fluids or lenses of rabbits dosed with Pb, despite the appearance of high concentrations in blood, liver, and brain. We were also unable to detect it in lenses from cattle, horses, dogs, or four elderly humans. The possibility of environmental lead exerting toxic effects in the eye thus appears to be minimal.