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Synthesis of Morphlinotetrahydrothieno[2,3‐c]Isoquinolines

 

作者: Adel M. Kamal El‐Dean,   Shaban M. Radwan,   Remon M. Zaki,  

 

期刊: Journal of the Chinese Chemical Society  （WILEY Available online 2008）
卷期: Volume 55, issue 6  

页码: 1290-1299

 

ISSN:0009-4536

 

年代: 2008

 

DOI:10.1002/jccs.200800193

 

出版商: WILEY‐VCH Verlag

 

关键词: Synthesis;Reactions;Tetrahydroisoquinolines;Thienotetrahydroisoquinolines;Pyrimidothienotetrahydroisoquinolines

 

数据来源: WILEY

 

摘要:

Abstract1‐Morpholin‐4‐yl‐5,6,7,8‐tetrahydroisoquinoline‐4‐carbonitrile (2) was synthesized from 3‐amino‐1‐thioxo‐5,6,7,8‐tetrahydro‐1H‐isothiochromene‐4‐carbonitrile (1) and used as starting material to synthesize many thienotetrahydroisoquinolines (4), which in turn were used in the synthesis of many pyrimi

 

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