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Association between Allele 1 of T102C Polymorphism, 5-Hydroxytryptamine 2a Receptor Gene and Schizophrenia in Chinese Males in Singapore

 

作者: A.H.N. Tay,   L.C.C. Lim,   W.L. Lee,   K.E. Wong,   L.Y. Wong,   W.F. Tsoi,  

 

期刊: Human Heredity  （Karger Available online 1997）
卷期: Volume 47, issue 5  

页码: 298-300

 

ISSN:0001-5652

 

年代: 1997

 

DOI:10.1159/000154428

 

出版商: S. Karger AG

 

关键词: Chinese male schizophrenics;5-Hydroxytryptamine 2a receptor polymorphism

 

数据来源: Karger

 

摘要:

The T102C polymorphism at the 5-hydroxytryptamine 2a receptor (5HTR2a) gene was studied in 101 Chinese male schizophrenics and 103 controls. Genotyping revealed a predominance of allele 1 among schizophrenics. This is in contrast to previous reports in Caucasians and Japanese which showed an association of allele 2 of this polymorphism with schizophrenia.

 

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