Hypothesis testing of diagnostic accuracy for multiple readers and multiple tests an anova approach with dependent observations
作者:
Nancy A. Obuchowski,
Howard E. Rockette,
期刊:
Communications in Statistics - Simulation and Computation
(Taylor Available online 1995)
卷期:
Volume 24,
issue 2
页码: 285-308
ISSN:0361-0918
年代: 1995
DOI:10.1080/03610919508813243
出版商: Marcel Dekker, Inc.
关键词: ROC curves;dependent observations;corrected F-statistic
数据来源: Taylor
摘要:
A method is proposed for comparing the accuracy of diagnostic tests that rely on a reader's subjective interpretation of the results. An ANOVA approach is applied where the dependencies between the readers' estimates of diagnostic accuracy are handled by adjusting the usual F statistic for theestimated correlation. The distribution of the resulting test statistic is evaluated. The problem is particularly relevant to diagnostic radiology where multi-reader studies of the indices associated with the ROC curve serve important roles in evaluating the efficacy of diagnostic tests.
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