The effects of the vesicular‐arbuscular mycorrhizal (VAM) fungusGlomus deserticola(Trappe, Bloss, and Menge) on growth and mineral element uptake of sorghum [Sorghum bicolor(L.) Moench] were investigated in greenhouse experiments with acid Cecil sandy clay loam (clayey, kaolinitic, thermic, Typic Hapludults) at five pH values (4.1 to 5.8). Control experiments consisted of sterile VAM inocula. Dry matter yields and mineral element uptake were markedly depressed at pH 4.1, were relatively high at pH 4.5, and remained fairly constant from pH 4.5 to 5.8 in mycorrhizal plants. Dry matter yields, root lengths, and mineral element contents of nonmycorrhizal plants increased as soil pH increased, and these characteristics were similar to mycorrhizal plants only after the soil was above pH 5.0 to 5.5. Mycorrhizal plants had higher total and efficiency uptake of mineral elements (shoot element content/root dry matter ratio) than nonmycorrhizal plants. Available Al in acid soils may have been detrimental to VAM infection with sorghum roots and for VAM fungal activity at low soil pH.