A GCN‐like response inCandida albicans.
作者:
Sarita Anne Pereira,
George P. Livi,
期刊:
Cell Biology International
(WILEY Available online 1995)
卷期:
Volume 19,
issue 1
页码: 65-70
ISSN:1065-6995
年代: 1995
DOI:10.1006/cbir.1995.1009
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
AbstractThe control of amino acid and purine biosynthesis in the yeast Saccharomyces cerevisiae is mediated by the transcriptional activator GCN4. We previously identified the presence of two putative GCN4 responsive elements (GCREs) in the promoter sequence of the Candida albicans ARO3 gene, which encodes an enzyme in the aromatic amino acid pathway. We now show that amino acid deprivation results in a dramatic rise in the steady‐state level of ARO3‐specific mRNA, indicative of a GCN‐like pathway in C. alb
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