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Drosophila EbonyMutants Have Altered Circadian Activity Rhythms but Normal Eclosion Rhythms

 

作者: NewbyLaurel M.,   JacksonF. Rob,  

 

期刊: Journal of Neurogenetics  (Taylor Available online 1991)
卷期: Volume 7, issue 2-3  

页码: 85-101

 

ISSN:0167-7063

 

年代: 1991

 

DOI:10.3109/01677069109066213

 

出版商: Taylor&Francis

 

关键词: Drosophila melanogaster;circadian rhythms;temperature compensation;visual defects;ebony;dopamine

 

数据来源: Taylor

 

摘要:

Drosophila ebonymutants exhibit a syndrome of morphological and behavioral phenotypes that include an abnormally dark body color and defects in visual and courtship responses. We now show that mutants carrying any one of fiveebonyalleles display complex and variable locomotor activity rhythms. Although in the most extreme cases activity is essentially aperiodic, many individuals express short- and/or long-period activity components. Three differentebonymutants (e, e1, ande11) express free-running rhythmicity in a temperature-dependent manner; activity rhythms are robust at 28°C. but weak or absent at 20°C. Even while maintained in a light-dark (LD) cycle,ebonyhomozygotes characteristically display extremely disorganized patterns of activity: some individuals entrain with an apparently abnormal phase and/or express multiple rhythmic components. Interestingly, the visual system mutationnorpApartially suppresses effects of thee1allele, which suggests that aberrant visual system inputs might contribute to the rhythm deficits ofebonymutants. In contrast to their effects on the locomotor activity rhythm,ebonymutations have no apparent impact on the circadian rhythm of adult eclosion, and thus exert rhythm-specific effects on circadian periodicity.

 

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