Neuropeptides in the Middle Ear Mucosa
作者:
J. Ylikoski,
P. Panula,
期刊:
ORL
(Karger Available online 1988)
卷期:
Volume 50,
issue 3
页码: 176-182
ISSN:0301-1569
年代: 1988
DOI:10.1159/000275987
出版商: S. Karger AG
关键词: Immunohistochemistry;Neuropeptides;Middle ear;Tympanic nerve
数据来源: Karger
摘要:
Substance P- and neuropeptide Y-like immunoreactivity was demonstrated by immunohistochemical methods in mucosal specimens from the middle ear cleft of the guinea pig and rat. Substance P-like immunoreactivity was seen in corresponding specimens of the rabbit. Substance P-like immunoreactivity was also demonstrated in the tympanic nerve of various animal species and man. These specimens also showed weak immunoreactivity for bombesin. The findings suggest the presence of substance P in the tympanic nerve. Theoretically substance P may act in the middle ear cleft mucosa in several ways. One possibility is its putative role in the neurochemical control of the middle ear aeration. Another hypothetical possibility is a role in the neurogenic inflammation after noxious stimulation of the middle ear mucosa.
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