Superantigens and Their Role in Disease
作者:
KotzinBrian L.,
期刊:
Hospital Practice
(Taylor Available online 1994)
卷期:
Volume 29,
issue 11
页码: 59-70
ISSN:2154-8331
年代: 1994
DOI:10.1080/21548331.1994.11443108
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Because superantigens bind to extremely large numbers of T cells, they are useful for investigating the immune system. Moreover, they appear to have diverse pathologic roles. They may be responsible for massive cytokine release in toxic shock, activate self-reactive T cells in Kawasaki disease and rheumatoid arthritis, and participate in immune tolerance and deficiency.
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