Cyclo-oxygenase and lipoxygenase pathways in cynomolgus and rhesus monkey conjunctiva, anterior uvea and eyelids
作者:
KulkarniPrasad S.,
KaufmanPaul L.,
SrinivasanB. Dobli,
期刊:
Current Eye Research
(Taylor Available online 1987)
卷期:
Volume 6,
issue 6
页码: 801-808
ISSN:0271-3683
年代: 1987
DOI:10.3109/02713688709034847
出版商: Taylor&Francis
数据来源: Taylor
摘要:
The capacity of cynomolgus and rhesus monkey conjunctiva, anterior uvea and eyelids to synthesize cyclo-oxygenase and lipoxygenase products from arachidonic acid was assessed. Both conjunctiva and eyelid tissues of cynomolgus and rhesus monkeys synthesized detectable amounts of cyclo-oxygenase and lipoxygenase products, indicating the presence of cyclo-oxygenase and 5-and 12-lipoxygenase activities in these tissues. In comparison, cynomolgus anterior uvea synthesized a considerably lesser amount of cyclo-oxygenase products. The cyclo-oxygenase activity was considerably greater than the lipoxygenase activity in cynomolgus and rhesus conjunctiva and eyelids.
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