The origin of biexponential T2 relaxation in muscle water
作者:
William C. Cole,
Adrian D. Leblanc,
Satish G. Jhingran,
期刊:
Magnetic Resonance in Medicine
(WILEY Available online 1993)
卷期:
Volume 29,
issue 1
页码: 19-24
ISSN:0740-3194
年代: 1993
DOI:10.1002/mrm.1910290106
出版商: Wiley Subscription Services, Inc., A Wiley Company
数据来源: WILEY
摘要:
AbstractTwo theories have been proposed to explain the multiexponential transverse relaxation of muscle water protons: “anatomical” and “chemical” compartmentation. In an attempt to obtain evidence to support one or the other of these two theories, interstitial and intracellular macromolecular preparations were studied and compared with rat muscle tissue by proton NMR transverse relaxation (T2) measurements. All macromolecule preparations displayed monoexponential T2 decay. Membrane alteration with DMSO/glycerin did not eliminate the biexponential T2 decay of muscle tissue. Maceration converted biexponential T2 decay of muscle tissue to single exponential decay. It is concluded that the observed two component exponential T2 decay of muscle represents anatomical compartmentation of tissue water, probably intracellular versus extrac
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