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EVALUATION OF MODEL FOR STRATUM CORNEUM LIPID BARRIER AGAINST STEROID DIFFUSION

 

作者: M. Trotta,   M.E. Carlotti,   M. Gallarate,  

 

期刊: Journal of Dispersion Science and Technology  （Taylor Available online 1999）
卷期: Volume 20, issue 7  

页码: 1831-1847

 

ISSN:0193-2691

 

年代: 1999

 

DOI:10.1080/01932699908943893

 

出版商: Taylor & Francis Group

 

数据来源: Taylor

 

摘要:

The ability of three matrices to model the barrier properties of the lipid domain of stratum corneum (SC) against permeation of seven steroids was studied. Model matrices were water and oleic acid/oleate; a mixture of unsaturated and saturated fatty acids/soap; or a more complex matrix also containing phospholipids, sphingolipids, cholesterol and ceramides.

 

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