Toxic megacolon secondary to pseudomembranous colitis
作者:
John Cone,
William Wetzel,
期刊:
Diseases of the Colon & Rectum
(OVID Available online 1982)
卷期:
Volume 25,
issue 5
页码: 478-482
ISSN:0012-3706
年代: 1982
出版商: OVID
关键词: Colitis, pseudomembranous, antibiotic‐induced;Megacolon, toxic
数据来源: OVID
摘要:
&NA;Toxic megacolon has rarely been reported in the course of antibiotic‐induced pseudomembranous colitis. We have been able to collect 20 cases from the literature and add one new case. The mortality in the collected series was 33 per cent. The critical factor in improving survival is early recognition of the pseudomembranous colitis. Most patients can be managed medically by removal of the offending antibiotic, bowel rest, vancomycin, and steroids. If toxic megacolon develops in the face of appropriate medical management, an aggressive surgical approach is indicated, as with ulcerative colitis. Subtotal colectomy appears to be the procedure of choice.
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