Morphologic Effects of Experimental Distention of Equine Small Intestine
作者:
DOUGLAS ALLEN,
NATHANIEL A. WHITE II,
DAVID E. TYLER,
期刊:
Veterinary Surgery
(WILEY Available online 1988)
卷期:
Volume 17,
issue 1
页码: 10-14
ISSN:0161-3499
年代: 1988
DOI:10.1111/j.1532-950X.1988.tb00269.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
The morphologic effects of induced intraluminal hydrostatic pressures (IHPs) of 0, 9, and 18 cm H2O were evaluated in 33 isolated equine jejunal segments. Fifteen segments were distended with Tyrode's solution for 1 hour and nine segments for 4 hours. Tyrode's solution was added as needed to maintain the prescribed pressures. Nine other segments were left undisturbed for 4 hours after the initial distention period. On decompression of the intestinal segments, progressive peristaltic contractions resumed in all segments. Evaluation of intestinal sections by light microscopy and transmission electron microscopy showed edema of the villi and submucosa and separation of the epithelial cells adjacent to the basement membrane in all segments. The epithelial cell necrosis found in ischemic intestine was not seen. This study indicates that the necrosis found at the villous tips in distended sections of small intestine remote from the site of obstruction cannot be reproduced by IHP increases of 4 hours duration.
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