SYNOPSISA randomized, double-blind trial evaluating the efficacy of montelukast, a leukotriene receptor antagonist, versus placebo in mild-to-moderate asthma, showed efficacy for this new therapy.SOURCEReiss TF et al. Montelukast, a once-daily leukotriene receptor antagonist, in the treatment of chronic asthma. Arch Intern Med 1998;158:1213–20.