A synthesis of the cyclohexapyrrolizidines32and33is described; the structure of the latter was determined by X-ray crystallography. It is anticipated that this synthesis will serve as a model for the construction of a similar pyrrolizidine system during a projected synthesis of thelepogine2.A convenient method for theC-methylation of cyclic vinylogous amides is also described. This procedure, which is similar to published procedures, affords high yields of methylated product and is regiospecific.