AbstractThe isolation of tetramine (tetramethylammonium hydroxide) as the iodide from the root ofCourbonia virgarais described, and its distribution in various pans of the plant is recorded. The presence also of di‐ and trimethylmine has been proved, and of quaternary bases other than tetramine induced. The carbohydrate material of the root is partly sucrose and partly araban, reducing sugars and starch being absent; while that of the seeds is mainly starch together with a little pentosan, sucrose and reducing sugars being absent. The constants and fatty acid composition of the root fat have been determined and the composition of the ash of the root is also given.We are indebted to the District Commissioner, Yirol, for providing material j to Dr. F. W. Andrews for botanical data; to Riad Eff. Mansour and Ahmed Eff. Hassan Zaki for much technical assistance; and to the Director, Sudan Medical Service, for permission to publish this pape