Spread of HSV-1 to the mouse eye after inoculation in the skin of the snout requires an intact nerve supply to the inoculation site
作者:
ShimeldC.,
DysonH.,
LewkowiczS.,
HillT. J.,
BlythW. A.,
EastyD. L.,
期刊:
Current Eye Research
(Taylor Available online 1987)
卷期:
Volume 6,
issue 1
页码: 9-12
ISSN:0271-3683
年代: 1987
DOI:10.3109/02713688709020061
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Infection of the eye following inoculation of herpes simplex virus on the skin of the snout was monitored using slit lamp examination of the eye, isolation of virus from eyewashings and identification of virus antigens in whole corneal epithelial sheets by peroxidase-antiperoxidase staining. Infection of the eye was prevented by removing a section of the sensory nerves which supply the inoculation site. This provided evidence that spread from the skin of the snout to the eye occurred via the nerves.
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