The Art of Clinical Management in Pharmacologic Trials With Depressed Elderly PatientsLessons from the Pittsburgh Study of Maintenance Therapies in Late‐Life Depression
作者:
Mark Miller,
Ellen Frank,
Charles Reynolds,
期刊:
American Journal of Geriatric Psychiatry
(OVID Available online 1999)
卷期:
Volume 7,
issue 3
页码: 228-234
ISSN:1064-7481
年代: 1999
出版商: OVID
关键词: Depression;Antidepressants;Clinical Trials
数据来源: OVID
摘要:
The authors outline the clinical management methods used in a long-term study of depressed elderly patients and comment on the positive aspects of such interventions on the successful recruitment and retention of subjects. Psychosocial or clinical management (CM) is the “glue” that holds a successful drug trial together. CM is recognized to be an essential element for success in drug trials for geriatric depression. The authors also discuss potentially negative aspects of comprehensive CM, such as those obscuring a psychotherapeutic effect in comparative studies.
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