Ultrastructure of the Adenohypophysis in a Case of Cyclopia
作者:
Hiroshi SUMIDA,
Naotaka AKIMOTO,
Naohiko INOUE,
Yukio SATOW,
期刊:
Congenital Anomalies
(WILEY Available online 1991)
卷期:
Volume 31,
issue 1
页码: 47-53
ISSN:0914-3505
年代: 1991
DOI:10.1111/j.1741-4520.1991.tb00358.x
出版商: Blackwell Publishing Ltd
关键词: cyclopia;hypophysis;endocrine;electron microscopy
数据来源: WILEY
摘要:
AbstractThe adenohypophysis of a newborn with cyclopia was examined by electron microscopy. The hypophysis was normal in size and shape in the present case. Electron microscopy, however, showed degenerating cells in the adenohypophysis. These cells had small number of granules and cytoplasmic organelles, and the concentric membranous structure, but were not considered as necrotic cells. These findings may indicate overproduction of hormones by the damage of the negative feedback system. No remarkable change, however, was observed in the endocrine organs by light microscopy. Thus, the possible disorder of the hormone production might not be severe enough to cause abnormal formation of the endocrine system in the present case.
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