Comparability of RP-HPLC Retention Indices of Drugs in Three Databases
作者:
Maciej Bogusz,
DennisW. Hill,
Astrid Rehorek,
期刊:
Journal of Liquid Chromatography & Related Technologies
(Taylor Available online 1996)
卷期:
Volume 19,
issue 8
页码: 1291-1316
ISSN:1082-6076
年代: 1996
DOI:10.1080/10826079608006319
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
Three databases of HPLC retention indices in the 1-nitroalkane scale were recently established (IFM = Institute of Forensic Medicine, MCL = Microchemistry Laboratory, MTSS = Merck Tox Screening System). In two of them (IFM and MTSS) virtually identical chromatographic conditions were applied but different RP-columns. In the third system (MCL) a different column and different elution conditions were used. Among a total of 1149 drugs examined in all three labs, 258 drugs were common for IFM and MTSS, 179 were common for MCL and MTSS, 162 were common for IFM and MCL, and 135 drugs were common for all three databases.
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