86-Rb Efflux in normal and cataractous human lenses
作者:
GandolfiStefano A.,
TombaMaria Carla,
MarainiGiovanni,
期刊:
Current Eye Research
(Taylor Available online 1985)
卷期:
Volume 4,
issue 7
页码: 753-758
ISSN:0271-3683
年代: 1985
DOI:10.3109/02713688509020030
出版商: Taylor&Francis
数据来源: Taylor
摘要:
86Rb efflux has been studied in normal lenses and in human senile cataracts. The rate constant (Ki) of the efflux gradually increases in cataractous lenses with progression of lens damage. Efflux experiments run in the presence of BaC12 suggest that a progressive activation of BaC12 inhibitable efflux routes occurs in cataractous lenses. In the final stages of opacification the ineffectiveness of BaC12 enriched or Ca++ free media on the efflux suggests that a direct disruption of the lens membranes has occurred.
点击下载:
PDF (413KB)
返 回