Disease Specificity of Antibodies to Poly (Adp-Ribose); Their Relationships to Anti-DNA Antibodies and to Disease Activity in Lupus
作者:
Le PageSusan H.,
DudeneyCarol,
ShallS.,
ShoenfeldY.,
IsenbergD. A.,
期刊:
Autoimmunity
(Taylor Available online 1990)
卷期:
Volume 5,
issue 3
页码: 169-177
ISSN:0891-6934
年代: 1990
DOI:10.3109/08916939009002975
出版商: Taylor&Francis
关键词: Anti poly (ADP-ribose) antibodies;disease specificity;anti-DNA antibodies
数据来源: Taylor
摘要:
In this study we have measured the level of anti poly (ADP-ribose) antibodies in the sera of a number of patients with SLE and their relatives, patients with a wide variety of other autoimmune and infectious diseases, and a group of normal healthy controls.It was found that these antibodies were not disease specific but were present in nine out of thirteen groups tested in significant numbers.The levels of anti poly (ADP-ribose) antibodies and anti DNA antibodies in SLE patients bled serially were also measured. The level of these antibodies fluctuated in parallel in many of these patients, although the anti poly (ADP-ribose) antibodies reflected disease activity more accurately in some.
点击下载:
PDF (452KB)
返 回