Exacerbation of Pulmonary Sarcoidosis After Liver Transplantation
作者:
Oren Shibolet,
Yossi Kalish,
Dana Wolf,
Orit Pappo,
Uri Laxer,
Neville Berkman,
Dorit Shaham,
Yaffa Ashur,
Yaron Ilan,
期刊:
Journal of Clinical Gastroenterology
(OVID Available online 2002)
卷期:
Volume 35,
issue 4
页码: 356-358
ISSN:0192-0790
年代: 2002
出版商: OVID
关键词: Sarcoidosis;Liver transplantation
数据来源: OVID
摘要:
Patients with hepatic sarcoidosis rarely require orthotopic liver transplantation (OLT). Progression of granulomatous activity involving other organs after OLT has rarely been described. We describe a 32-year-old woman who underwent liver transplantation for sarcoidosis-associated end-stage liver disease. She presented 4 years later with shortness of breath, hilar lymphadenopathy, and interstitial lung abnormalities. Liver functions were normal. Open lung biopsy results revealed granulomata compatible with sarcoidosis. The patient made a complete recovery after corticosteroid treatment. To the best of our knowledge, this is a first description of severe exacerbation of pulmonary sarcoidosis in an immunosuppressed patient who underwent liver transplantation for sarcoidosis-associated liver disease.
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