By developing and applying certain results on boundary crossing probabilities of generalized likelihood ratio statistics in multiparameter exponential families, we show that Lai's (1988a) modification of Schwarz's (1962) sequential likelihood ratio tests of one-sided hypotheses in the one-parameter case can be extended to general hypotheses in the multiparameter case. Such tests are shown to be asymptotically optimal, from both frequentist and Bayesian points of view, and numerical results are also given to demonstrate their performance.