Effects of rhGM-CSF on Myeloid Clonogenic Cells in Acute Myelogenous Leukemia Patients
作者:
PreislerHarvey,
LarsonRichard,
BanavaliShripad,
YinMoying,
LiYa Qin,
BanerjeeMekhala,
GopalVenu,
RazaAzra,
期刊:
Leukemia&Lymphoma
(Taylor Available online 1993)
卷期:
Volume 10,
issue 3
页码: 183-186
ISSN:1042-8194
年代: 1993
DOI:10.3109/10428199309145881
出版商: Taylor&Francis
关键词: rhGM-CSF;clonogenic cells;AML
数据来源: Taylor
摘要:
The effects of rhGM-CSF in vivo on the myeloid clonogenic cells present in 6 AML patients was evaluated. The relative number of clonogenic cells fell in 4 of the 6 patients. The effects of rhGM-CSF on the percentage of clonogenic cells in S phase and the sensitivity of clonogenic cells to cytosine arabinoside varied among the patients. These effects were not related to the effects of rhGM-CSF on the white blood cell count or on the proliferative rate of the leukemia cell population as a whole.
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