POLAR INTERACTIONS OF HYALURONIC ACID -EXPERIMENTS AND MOLECULAR DYNAMICS SIMULATIONS-
作者:
J. Kaufmann,
D. Wiegel,
K. Arnold,
期刊:
Journal of Dispersion Science and Technology
(Taylor Available online 1998)
卷期:
Volume 19,
issue 6-7
页码: 979-1001
ISSN:0193-2691
年代: 1998
DOI:10.1080/01932699808913227
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
To study the polar interactions of the cartilage component hyaluronate (HA) contact angle measurements of polymer films of sodium hyaluronate and of the free hyaluronic acid with different probe liquids and theoretical investigations with molecular dynamics simulation (MD) on polymer segments in aqueous environment were performed. For the designation of contact angles water, formamid, glycerol and α-bromnaphthalene as probe liquids were used. The surface tension components were calculated on the basis of the theory of van Oss using the Young equation. Experimental investigations were done with air dried layers of the sodium salt of HA whose surface has been formed at the interface to the air resp. glass support. Whereas the surface polymer/air is characterized by small, but non-zero values for γ•and γ-the surface polymer/glass tends to have γ-monopolar properties. In opposite to the salt form of HA a strong repulsion of chains and high γ-monopolarity was measured for the protonated form.
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