Biodegradation data evaluation for structure/biodegradability relations
作者:
Philip H. Howard,
Amy E. Hueber,
Robert S. Boethling,
期刊:
Environmental Toxicology and Chemistry
(WILEY Available online 1987)
卷期:
Volume 6,
issue 1
页码: 1-10
ISSN:0730-7268
年代: 1987
DOI:10.1002/etc.5620060101
出版商: Wiley Periodicals, Inc.
关键词: Biodegradation;Evaluation;Structure/activity
数据来源: WILEY
摘要:
AbstractPrevious attempts at structure/biodegradability relations (SBRs) and available biodegradation data are reviewed and it is concluded that (1) not enough rate data on large numbers of chemicals are available to develop quantitative SBRs and (2) attempted qualitative SBRs have suffered from either poor documentation of the biodegradation evaluation or they have used limited biodegradation test data. Because of the poor reproducibility of biodegradation tests, a weight‐of‐evidence evaluation procedure is proposed. A system for collecting and evaluating biodegradation data from screening tests, biological treatment simulations, grab sample tests and field studies is described and study‐specific and summary biodegradability codes in combination with reliability codes are developed that can be used for structure/biodegradability rela
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