Implantation of Fetal Thymus and Sympathetic Ganglion within the Anterior Eye Chamber in Mice, to Study Neuro-Immune Interaction in Thymic Development
作者:
Upendra Singh,
Jamal Fatani,
Lalit Mehta,
Abdul Majeed Mohajir,
期刊:
Cells Tissues Organs
(Karger Available online 1990)
卷期:
Volume 137,
issue 1
页码: 54-58
ISSN:1422-6405
年代: 1990
DOI:10.1159/000146858
出版商: S. Karger AG
关键词: Lymphopoiesis;Anterior eye chamber;Implantation;Adrenergic innervation;Sympathetic ganglion;Fetal thymus
数据来源: Karger
摘要:
In this study 13- to 14-day fetal thymic lobes were implanted within the anterior eye chambers in mice either with or without a syngeneic newborn sympathetic ganglion. It was observed after 6 weeks of implantation that the thymic lobes that grew with the ganglia had fewer lymphoid cells than their counterparts which were grown without the ganglia. The cells that developed within the thymic lobes were Thy-1- and peanut agglutinin-positive. The thymic lobes that grew with sympathetic ganglia also showed the presence of adrenergic nerves, perhaps due to reinnervation of the thymic grafts from the ganglia.
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