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Detection of Complexes Containing 70S RNA and Reverse Transcriptase in Human Leukemic Plasma

 

作者: Abraham Yaniv,   Subhash C. Gulati,   Arsene Burny,   Sol Spiegelman,  

 

期刊: Intervirology  （Karger Available online 1973）
卷期: Volume 1, issue 5-6  

页码: 317-328

 

ISSN:0300-5526

 

年代: 1973

 

DOI:10.1159/000148860

 

出版商: S. Karger AG

 

关键词: 70S RNA;Reverse transcriptase;Human leukemia;Murine leukemia virus relatednessf

 

数据来源: Karger

 

摘要:

Complexes containing 70S RNA and RNA-directed DNA polymerase were detected in 74% of the human leukemic plasmas, whereas none was observed in normal plasmas. The DNA product synthesized by these complexes hybridized to the RNA of Rauscher leukemia virus and to RNA obtained from leukemic cells and did not hybridize to the RNA of normal leukocytes or to theRNA of the unrelated avian myeloblastosis virus.

 

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