Central venous access is frequently used for monitoring and administration of drugs in the intensive care unit, and for administration of parenteral nutrition. The improving results of neonatal surgery have closely followed the evolution of neonatal intensive care and parenteral nutrition. Nutritional support by the parenteral route is required in the majority of cases for only a few weeks. Percutaneous sialastic long line introduced into a central vein through a peripheral venous puncture has emerged as one of the most popular techniques for delivery of parenteral nutrition in neonates.