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Predictive Value of the Fluorescent Cytoprint Assay (FCA): A Retrospective Correlation Study of In Vitro Chemosensitivity and Individual Responses to Chemotherapy

 

作者: LeoneLouis A.,   MeitnerPatricia A.,   MyersThomas J.,   GraceWilliam R.,   GajewskiWalter H.,   FingertHoward J.,   RotmanBoris,  

 

期刊: Cancer Investigation  （Taylor Available online 1991）
卷期: Volume 9, issue 5  

页码: 491-503

 

ISSN:0735-7907

 

年代: 1991

 

DOI:10.3109/07357909109018947

 

出版商: Taylor&Francis

 

数据来源: Taylor

 

摘要:

AbstractThe potential clinical usefulness of the fluorescent cytoprint assay (FCA) was assessed retrospectively in 73 cancer patients by correlating individual tumor chemosensitivity in vitro with responses to chemotherapy. The data show that the FCA has a sensitivity of 98%, specificity of 81%, and predictive accuracies of 85% and 97% for positive and negative clinical responses, respectively.

 

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