Multifunctional Zwitterion-Exchange Stationary Phase for HPLC
作者:
Tsong-Yung Chou,
Mei-Hui Yang,
期刊:
Journal of Liquid Chromatography & Related Technologies
(Taylor Available online 1996)
卷期:
Volume 19,
issue 17-18
页码: 2985-2996
ISSN:1082-6076
年代: 1996
DOI:10.1080/10826079608015121
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
A zwitterion-exchange stationary phase (ZIXSP) was prepared for the separation of the mixture of organic bases, organic acids and amino acids by high performance liquid chromatography (HPLC). It was synthesized by the reaction of cyanuric chloride with sulfanilic acid and then bonded onto the silica gel on which the silane coupling agent was prebonded. The chromatographic behaviours of the prepared ZIXSP revealed that the capacity factors of each analyte varied with the pH value of the mobile phase. By applying the concept of acid-base equilibrium the correlation between the capacity factor on the ZIXSP and pH of the mobile phase could be explained reasonably. Based on our results, it is concluded that ZIXSP is a zwitterion exchanger that additionally provides π-π charge-transfer interaction and hydrophobic interaction functions.
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