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Correlative and Mechanistic QSAR Models in Toxicology

 

作者: R.L. Lipnick,  

 

期刊: SAR and QSAR in Environmental Research  （Taylor Available online 1999）
卷期: Volume 10, issue 2-3  

页码: 239-248

 

ISSN:1062-936X

 

年代: 1999

 

DOI:10.1080/10629369908039178

 

出版商: Taylor & Francis Group

 

关键词: Correlative;mechanistic;QSAR;EPA;history;aquatic

 

数据来源: Taylor

 

摘要:

An outline is provided on the development and use of correlative and mechanistic approaches to predictive toxicology, with particular emphasis on the experience at the U.S. EPA as applied to assessing the potential hazard posed by new industrial chemicals for which little or no test data are provided under the Toxic Substances Control Act. This information is presented with a historical perspective.

 

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