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ASCORBIC ACID AND PLASMA LIPIDS

 

作者: Paul,   Jacques Sandra,   Sulsky Gayle,   Perrone Ernst,  

 

期刊: Epidemiology  (OVID Available online 1994)
卷期: Volume 5, issue 1  

页码: 19-26

 

ISSN:1044-3983

 

年代: 1994

 

出版商: OVID

 

关键词: ascorbic acid;cholesterol levels;lipoproteins;HDL cholesterol;LDL cholesterol;triglycerides;gender;alcohol drinking

 

数据来源: OVID

 

摘要:

We examined the association between plasma lipids and total ascorbic acid in 256 men and 221 women age 20–65 years. Among men, we observed that high-density lipoprotein (HDL) cholesterol was 2.1 mg per dl higher, total:HDL cholesterol was 5.4% lower, total cholesterol was 4.8 mg per dl lower, low-density lipoprotein (LDL) cholesterol was 5.6 mg per dl lower, and triglyceride was 5.2% lower for each 0.5 mg per dl increment in ascorbic acid. The association between ascorbic acid and total:HDL cholesterol ratio in men was modified by glucose concentration. Among women, we observed that HDL cholesterol was 14.9 mg per dl higher for women with ascorbic acid levels ≤1.05 mg per dl and 0.9 mg per dl lower for women with ascorbic acid levels >1.05mg per dl for each 0.5 mg per dl increment in ascorbic acid. Total:HDL cholesterol ratio was 10.9% lower for women with ascorbic acid concentrations ≤1.45 mg per dl and 0.6% higher for women with ascorbic acid concentrations >1.45 mg per dl for each 0.5 mg per dl increment. The associations among ascorbic acid concentration, total and LDL cholesterol, and triglyceride concentrations were weak or absent among women. These results are consistent with earlier observations relating ascorbic acid and HDL cholesterol and indicate that ascorbic acid might also be related to total and LDL cholesterol concentrations in men.

 

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