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Extrapyramidal Syndrome and Depression Induced by Flunarizine

 

作者: A. Lugaresi,   P. Montagna,   R. Gallassi,   E. Lugaresi,  

 

期刊: European Neurology  （Karger Available online 1988）
卷期: Volume 28, issue 4  

页码: 208-211

 

ISSN:0014-3022

 

年代: 1988

 

DOI:10.1159/000116268

 

出版商: S. Karger AG

 

关键词: Flunarizine;Elderly people;Extrapyramidal syndrome;Depression

 

数据来源: Karger

 

摘要:

Apathy, mood depression and extrapyramidal signs consisting of akinesia, amimia, gait apraxia, slight rigidity and tremor were induced in 10 patients by long-term treatment with flunarizine for trivial complaints. These symptoms suggest a mild antidopaminergic activity of flunarizine. Long-term administration of flunarizine should be avoided particularly in the elderly and in patients with extrapyramidal disorders.

 

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